ICSI clinics in Prague

Clayo Clinic is an independent, family-run fertility centre in Prague 5 - Smíchov, founded in 2023 by Dr. Daniel Hlinka PhD, a pioneer of human embryology in the former Czechoslovakia who performed the country's first ICSI fertilisation in 1993. Dr. Hlinka's innovations - including the OptimICSI method, which uses polarisation microscopy to identify peak oocyte maturity before fertilisation, as well as the introduction of MESA/TESE, vitrification and time-lapse monitoring in the Czech Republic - have contributed to the birth of more than 5,000 children. Unusually, the clinic accepts patients with lower chances of conception that other centres may turn away, offering a transparent, solution-focused approach and partial cost compensation if a cycle does not result in pregnancy. Clayo is ISO 9001 certified, led by ESHRE Senior Embryologist Dr. Hlinka (Head of Laboratory) and Head Physician MUDr. Radka Jarošová, with IVF gynaecologists MUDr. Jan Šulc, MUDr. Martin Hrehorčák PhD and MUDr. Marina Tomilova, Senior Embryologist Ing. Kateřina Vybíralová, and a multilingual coordinator team.

FertiCare was founded by Dr. Petr Uher, a member of the team behind the first Czech child conceived via assisted reproduction (1982). With clinics in Prague, Karlovy Vary, and Znojmo, FertiCare offers comprehensive male and female fertility treatment. The Prague headquarters features a state-of-the-art laboratory, and the Karlovy Vary branch allows patients to combine IVF treatment with the world-famous spa town. Free initial consultations are offered at all three locations.

FertilityPort Prague was purpose-built with international patients in mind. Located in a calm area near the Vltava river in Prague 8, with parking and a café on site, the clinic focuses exclusively on assisting couples from abroad with their fertility journey. The team, led by Dr. Vlček, Dr. Polášková, and Dr. Budka, brings extensive experience from major IVF centres in the Czech Republic and internationally. The clinic maintains a large, meticulously screened donor database with zero waiting time for egg or sperm donation, and coordinators including Daniela, Milica, and Hana are repeatedly praised by patients for rapid, compassionate, personalised communication. Advanced laboratory methods include EmbryoScope+ time-lapse monitoring, dividing spindle visualisation, and EmbryoGlue. Airport transfers and accommodation recommendations are offered as standard.

Gynem is a boutique private fertility clinic in Prague 8, founded in 2013 by head physician Dr Milan Mrázek, MD, PhD, MBA (30+ years in reproductive medicine) together with his son and co-founder Dr Martin Mrázek, MBA. The clinic is built around five stated values: the human touch, safety, results, proficiency and a personal coordinator for every patient. International patients get a dedicated multilingual coordinator (English, German, French, Italian and Serbian speakers on the team) who stays with them from the first enquiry through to pregnancy confirmation. There is no waiting list and treatment can typically be started within days. Airport transfer and taxi to the first appointment are included in the Optimal and Maximum IVF packages. Gynem offers a full menu of assisted reproduction: IVF (Basic / Optimal / Maximum packages), fresh and frozen egg donation with blastocyst guarantee (Basic / Comfort / Premium), embryo donation, egg freezing, dual-stimulation IVF, tandem cycles, natural-cycle IVF, IUI, PGT-A / PGT-M, andrology (MESA/TESE), ERA endometrial receptivity testing and psychological counselling. Free initial online consultations are offered to all international patients.

ISCARE IVF is part of the ISCARE group, one of the largest private healthcare providers in the Czech Republic. Operating a premium, fully integrated fertility centre in Prague 7, ISCARE IVF offers a comprehensive spectrum of fertility treatments in a single location, including its own on-site genetics laboratory. The clinic is especially well regarded for its preimplantation genetic testing programme.

IVF CUBE is a well-established Prague clinic purpose-built for international patients, led by Medical Director Hana Višňová, MD, Ph.D. (practising reproductive medicine since 1997) and Head of Embryology Dr. Renata Hüttelová, Ph.D., MBA (in the field since 1994). The clinic reports cumulative success rates of 84%+ in the egg donation programme (pregnancy after a single egg collection) using ICSI, Assisted Hatching, blastocyst culture and single vitrification as standard on every cycle. Patients are guaranteed at least 8 eggs from the donor and, with a normal partner sperm result, at least 2 blastocyst-stage embryos - minimums that are typically exceeded. Every patient is assigned one dedicated doctor and a personal treatment coordinator (fluent in English, German, French and Italian) who is reachable 24/7 in urgent cases. There is no waiting list, no deposit and no hidden costs - the price list covers the full package. The clinic holds ISO 15189:2013 and ESHRE accreditations, is located in Prague 6 just 10 minutes from Prague Airport and 15 minutes from the centre, and participates regularly in international research studies.

Prague Fertility Centre (PFC) is one of the Czech Republic's most internationally recognised fertility clinics. With patients from 35+ countries, PFC combines a state-of-the-art embryology lab with a deeply personal approach, every patient gets their own dedicated IVF coordinator. The clinic reports helping up to 90% of couples achieve pregnancy within four treatment cycles, and offers free online consultations for international patients.

Pronatal is one of the longest-established fertility clinics in the Czech Republic, with almost three decades of experience in assisted reproduction. With multiple Prague locations and a reputation for compassionate, knowledgeable staff, Pronatal has guided thousands of couples to parenthood. Experienced with complex cases, recurrent miscarriage, and patients who have had previous failed cycles.

Founded in 1991, UNICA is the first institute of reproductive medicine in the Czech Republic and the only Czech IVF clinic to combine cutting-edge reproductive medicine with holistic therapies including acupuncture, yoga and physiotherapy. Led by Prof. MUDr. Zdeněk Malý, CSc., UNICA is a founding member of the International Fertility Alliance (IFA), an ESHRE member and holds a strategic partnership with Canada's McGill University. Success is measured as clinical pregnancy with a fetal heartbeat detected on ultrasound: 59.5% per embryo transfer, and cumulative Egg Donation success of 71.2% after the 1st complete cycle, 91.5% after 2 cycles and 96.5% after 3 cycles (2024 results). Egg Donation programmes are backed by a 100% money-back guarantee if no live birth is achieved, plus a 5 embryos guarantee. Same success rates and standard of care across both UNICA Prague and UNICA Brno sites.